The work begins with a look at historical themes, such as the analysis of metaphase chromosomes using microscopy and staining techniques, advances in which provided our first broad glimpse into the genetic anatomy of a malignant cell. Exploring themes involving oncogenes, such as by chromosomal translocations, other genome rearrangements and somatic mutations, this book is a review of the field of cancer genetics that presages a new era, as whole genome sequencing becomes more accessible. This volume collates world experts’ insights into the molecular biology of cancer chromosomes, their abnormalities and the subsequent cellular consequences. These take-home resources are critical to helping both providers and patients understand some of the basic concepts and applications of genetics and genomics.Ĭhromosomal Translocations And Genome Rearrangements In Cancer by Janet D. Appendices can be copied for reference and offered to patients. At the end of each section, a list of references is provided for additional information. Resources are included to assist in patient care, patient and professional education, and identification of specialty genetics services within the New York - Mid-Atlantic region. It also provides information about diagnosis of genetic disease, family history, newborn screening, and genetic counseling. The manual begins with a basic introduction to genetics concepts, followed by a description of the different types and applications of genetic tests. The purpose of this manual is to provide an educational genetics resource for individuals, families, and health professionals in the New York - Mid-Atlantic region and increase awareness of specialty care in genetics. We only index and link to content provided by other sites.
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